{"title":"Reproductive \u0026 Pregnancy Raw Biomaterials","description":null,"products":[{"product_id":"hcg","title":"Human Chorionic Gonadotropin (HCG) Antibody \u0026 Antigen","description":"\u003cstyle data-eximio-product-css=\"blue-v3\"\u003e .eximio-product-description { --eximio-blue: #1f5fbf; --eximio-blue-dark: #123e73; --eximio-blue-soft: #f4f8fd; --eximio-text: #334155; --eximio-overview-text: #365777; --eximio-muted: #64748b; --eximio-line: #dbe5f1; --eximio-surface: #f8fafc; width: 100%; max-width: none; margin: 0; color: var(--eximio-text); font-size: 16px; line-height: 1.72; -webkit-font-smoothing: antialiased; } .eximio-product-description, .eximio-product-description * { box-sizing: border-box; } .eximio-product-description .eximio-product-section { margin: 0; padding: 25px 0; border: 0; background: transparent; } .eximio-product-description .eximio-product-section:first-child { padding-top: 0; } .eximio-product-description .eximio-product-overview { padding-bottom: 30px; } .eximio-product-description .eximio-product-heading { position: static; display: block; margin: 0 0 17px; padding: 0 0 10px; color: var(--eximio-blue-dark); background: transparent; border: 0; border-bottom: 1px solid var(--eximio-line); border-radius: 0; font-size: clamp(19px, 1.7vw, 22px); font-weight: 650; line-height: 1.35; letter-spacing: -0.01em; } .eximio-product-description .eximio-product-heading::before, .eximio-product-description .eximio-product-heading::after { content: none !important; display: none !important; } .eximio-product-description p { margin: 0 0 13px; color: var(--eximio-text); background: transparent; } .eximio-product-description p:last-child { margin-bottom: 0; } .eximio-product-description .eximio-product-overview \u003e p { max-width: 920px; color: var(--eximio-overview-text); font-size: 17px; line-height: 1.82; } .eximio-product-description strong { color: var(--eximio-blue-dark); font-weight: 650; } .eximio-product-description ol, .eximio-product-description ul { margin: 10px 0 0; padding-left: 1.45em; } .eximio-product-description li { margin: 0 0 8px; padding-left: 4px; } .eximio-product-description li::marker { color: var(--eximio-blue); } .eximio-product-description .eximio-important-note, .eximio-product-description .eximio-background, .eximio-product-description .eximio-clinical-significance, .eximio-product-description .eximio-product-parameters, .eximio-product-description .eximio-application-scope, .eximio-product-description .eximio-storage { background: transparent; border: 0; border-radius: 0; } .eximio-product-description .eximio-product-table { width: 100%; max-width: 100%; margin: 16px 0 4px; border: 1px solid var(--eximio-line); border-radius: 8px; border-collapse: separate; border-spacing: 0; background: #ffffff; } .eximio-product-description .eximio-product-table th, .eximio-product-description .eximio-product-table td { padding: 12px 14px; border-right: 1px solid var(--eximio-line); border-bottom: 1px solid var(--eximio-line); vertical-align: top; text-align: left; font-size: 14px; line-height: 1.55; } .eximio-product-description .eximio-product-table th { color: var(--eximio-blue-dark); font-weight: 650; background: var(--eximio-blue-soft); } .eximio-product-description .eximio-product-table tbody td { background: #ffffff; } .eximio-product-description .eximio-product-table tbody tr:nth-child(even) td { background: var(--eximio-surface); } .eximio-product-description .eximio-product-table tr:last-child \u003e * { border-bottom: 0; } .eximio-product-description .eximio-product-table tr \u003e *:last-child { border-right: 0; } .eximio-product-description .eximio-product-table th[scope=\"row\"] { width: 32%; min-width: 150px; } @media (max-width: 749px) { .eximio-product-description { font-size: 15px; line-height: 1.68; } .eximio-product-description .eximio-product-section { padding: 21px 0; } .eximio-product-description .eximio-product-overview { padding-bottom: 25px; } .eximio-product-description .eximio-product-heading { margin-bottom: 13px; padding-bottom: 8px; font-size: 18px; } .eximio-product-description .eximio-product-overview \u003e p { font-size: 16px; line-height: 1.76; } .eximio-product-description .eximio-product-table { display: block; overflow-x: auto; -webkit-overflow-scrolling: touch; } .eximio-product-description .eximio-product-table th, .eximio-product-description .eximio-product-table td { min-width: 120px; padding: 10px 12px; font-size: 13px; } } \u003c\/style\u003e \u003cdiv class=\"eximio-product-description eximio-product-description--v3\"\u003e \u003cdiv class=\"eximio-product-section eximio-background\"\u003e \u003ch2 class=\"eximio-product-heading\"\u003eBackground\u003c\/h2\u003e \u003cp\u003eHuman chorionic gonadotropin (HCG) is a glycoprotein secreted by trophoblastic cells of the placenta.\u003c\/p\u003e \u003cp\u003eHuman chorionic gonadotropin (HCG) is synthesized by syncytiotrophoblast cells.\u003c\/p\u003e \u003cp\u003eWith a molecular weight of 36,700, the α subunit is similar to FSH (follicle-stimulating hormone), LH (luteinizing hormone) and TSH (thyroid stimulating hormone) secreted by the pituitary gland, so it can cross-react with each other, while the structure of β subunit is not similar.\u003c\/p\u003e \u003cp\u003eThe structure of β-HCG is similar to that of β-LH, but the last 24 amino acid extensions are not present in β-LH.\u003c\/p\u003e \u003c\/div\u003e \u003cdiv class=\"eximio-product-section eximio-clinical-significance\"\u003e \u003ch2 class=\"eximio-product-heading\"\u003eClinical Significance\u003c\/h2\u003e \u003cp\u003eThe examination of HCG is of great significance for the diagnosis of early pregnancy, as well as for the diagnosis, differentiation and course observation of pregnancy-related diseases and trophoblastic tumors.\u003c\/p\u003e \u003cp\u003e1. Diagnosis of early pregnancy: HCG can rise to more than 2500 mIU\/mL 35~50 days after pregnancy.\u003c\/p\u003e \u003cp\u003eUp to 80000 mIU\/mL in 60~70 days, urine HCG of multiple pregnancies is often higher than that of one pregnancy.\u003c\/p\u003e \u003cp\u003e2. Determination of abnormal pregnancy and placental function:\u003c\/p\u003e \u003cp\u003e3. Diagnosis and treatment monitoring of trophoblastic tumor\u003c\/p\u003e \u003cp\u003e4. Menopause, ovulation and bilateral oophorectomy can lead to the increase of luteinizing hormone, and the same composition of peptide chain between LH and HCG leads to the positive pregnancy test with anti-hcg antibody, which can be identified by monoclonal two-point enzyme immunoassay of ~HCG.\u003c\/p\u003e \u003cp\u003eEndocrine diseases such as pituitary diseases, hyperthyroidism, gynecological diseases such as ovarian cyst, uterine cancer and other HCG can also increase.\u003c\/p\u003e \u003c\/div\u003e \u003cdiv class=\"eximio-product-section eximio-product-parameters\" data-eximio-generated=\"product-info-xlsx\"\u003e \u003ch2 class=\"eximio-product-heading\"\u003eProduct Parameters\u003c\/h2\u003e \u003cdiv class=\"eximio-generated-table\" data-eximio-generated=\"product-info-xlsx\"\u003e\u003ctable class=\"eximio-product-specs eximio-product-table\"\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eMaterial \/ Clone\u003c\/th\u003e\n\u003cth\u003eType\u003c\/th\u003e\n\u003cth\u003eCode\u003c\/th\u003e\n\u003cth\u003eSource\u003c\/th\u003e\n\u003cth\u003eApplication\u003c\/th\u003e\n\u003cth\u003eRecommended Use\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eFSH-15G7\u003c\/td\u003e\n\u003ctd\u003emAb\u003c\/td\u003e\n\u003ctd\u003eFBHG1\u003c\/td\u003e\n\u003ctd\u003eMouse (Antibody)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003eCoating\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHCG-6B12(β chain)\u003c\/td\u003e\n\u003ctd\u003emAb\u003c\/td\u003e\n\u003ctd\u003eFBHG3\u003c\/td\u003e\n\u003ctd\u003eMouse (Antibody)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003eLabeling\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHCG Antibody\u003c\/td\u003e\n\u003ctd\u003emAb\u003c\/td\u003e\n\u003ctd\u003eABHG7\u003c\/td\u003e\n\u003ctd\u003eMouse (Antibody)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003e-\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHCG Antigen\u003c\/td\u003e\n\u003ctd\u003eAg\u003c\/td\u003e\n\u003ctd\u003eAAHG3\u003c\/td\u003e\n\u003ctd\u003eE. coli (Antigen)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003e-\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHCG Raw Material Set\u003c\/td\u003e\n\u003ctd\u003eRaw Material Set\u003c\/td\u003e\n\u003ctd\u003eRMHG4\u003c\/td\u003e\n\u003ctd\u003eMouse (Antibody)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003e-\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003c\/div\u003e \u003c\/div\u003e \u003c\/div\u003e","brand":"EXIMIO BIOTEC","offers":[{"title":"Default Title","offer_id":47429298487452,"sku":null,"price":0.0,"currency_code":"CNY","in_stock":true}]},{"product_id":"lh","title":"Luteinizing Hormone (LH) Antibody \u0026 Antigen","description":"\u003cstyle data-eximio-product-css=\"blue-v3\"\u003e .eximio-product-description { --eximio-blue: #1f5fbf; --eximio-blue-dark: #123e73; --eximio-blue-soft: #f4f8fd; --eximio-text: #334155; --eximio-overview-text: #365777; --eximio-muted: #64748b; --eximio-line: #dbe5f1; --eximio-surface: #f8fafc; width: 100%; max-width: none; margin: 0; color: var(--eximio-text); font-size: 16px; line-height: 1.72; -webkit-font-smoothing: antialiased; } .eximio-product-description, .eximio-product-description * { box-sizing: border-box; } .eximio-product-description .eximio-product-section { margin: 0; padding: 25px 0; border: 0; background: transparent; } .eximio-product-description .eximio-product-section:first-child { padding-top: 0; } .eximio-product-description .eximio-product-overview { padding-bottom: 30px; } .eximio-product-description .eximio-product-heading { position: static; display: block; margin: 0 0 17px; padding: 0 0 10px; color: var(--eximio-blue-dark); background: transparent; border: 0; border-bottom: 1px solid var(--eximio-line); border-radius: 0; font-size: clamp(19px, 1.7vw, 22px); font-weight: 650; line-height: 1.35; letter-spacing: -0.01em; } .eximio-product-description .eximio-product-heading::before, .eximio-product-description .eximio-product-heading::after { content: none !important; display: none !important; } .eximio-product-description p { margin: 0 0 13px; color: var(--eximio-text); background: transparent; } .eximio-product-description p:last-child { margin-bottom: 0; } .eximio-product-description .eximio-product-overview \u003e p { max-width: 920px; color: var(--eximio-overview-text); font-size: 17px; line-height: 1.82; } .eximio-product-description strong { color: var(--eximio-blue-dark); font-weight: 650; } .eximio-product-description ol, .eximio-product-description ul { margin: 10px 0 0; padding-left: 1.45em; } .eximio-product-description li { margin: 0 0 8px; padding-left: 4px; } .eximio-product-description li::marker { color: var(--eximio-blue); } .eximio-product-description .eximio-important-note, .eximio-product-description .eximio-background, .eximio-product-description .eximio-clinical-significance, .eximio-product-description .eximio-product-parameters, .eximio-product-description .eximio-application-scope, .eximio-product-description .eximio-storage { background: transparent; border: 0; border-radius: 0; } .eximio-product-description .eximio-product-table { width: 100%; max-width: 100%; margin: 16px 0 4px; border: 1px solid var(--eximio-line); border-radius: 8px; border-collapse: separate; border-spacing: 0; background: #ffffff; } .eximio-product-description .eximio-product-table th, .eximio-product-description .eximio-product-table td { padding: 12px 14px; border-right: 1px solid var(--eximio-line); border-bottom: 1px solid var(--eximio-line); vertical-align: top; text-align: left; font-size: 14px; line-height: 1.55; } .eximio-product-description .eximio-product-table th { color: var(--eximio-blue-dark); font-weight: 650; background: var(--eximio-blue-soft); } .eximio-product-description .eximio-product-table tbody td { background: #ffffff; } .eximio-product-description .eximio-product-table tbody tr:nth-child(even) td { background: var(--eximio-surface); } .eximio-product-description .eximio-product-table tr:last-child \u003e * { border-bottom: 0; } .eximio-product-description .eximio-product-table tr \u003e *:last-child { border-right: 0; } .eximio-product-description .eximio-product-table th[scope=\"row\"] { width: 32%; min-width: 150px; } @media (max-width: 749px) { .eximio-product-description { font-size: 15px; line-height: 1.68; } .eximio-product-description .eximio-product-section { padding: 21px 0; } .eximio-product-description .eximio-product-overview { padding-bottom: 25px; } .eximio-product-description .eximio-product-heading { margin-bottom: 13px; padding-bottom: 8px; font-size: 18px; } .eximio-product-description .eximio-product-overview \u003e p { font-size: 16px; line-height: 1.76; } .eximio-product-description .eximio-product-table { display: block; overflow-x: auto; -webkit-overflow-scrolling: touch; } .eximio-product-description .eximio-product-table th, .eximio-product-description .eximio-product-table td { min-width: 120px; padding: 10px 12px; font-size: 13px; } } \u003c\/style\u003e \u003cdiv class=\"eximio-product-description eximio-product-description--v3\"\u003e \u003cdiv class=\"eximio-product-section eximio-background\"\u003e \u003ch2 class=\"eximio-product-heading\"\u003eBackground\u003c\/h2\u003e \u003cp\u003eLuteinizing hormone (LH) is a glycoprotein gonadotropin secreted by adenohypophysis cells that promotes the conversion of cholesterol into sex hormones in gonadal cells.\u003c\/p\u003e \u003cp\u003eFor women, follicle-stimulating hormone (FSH) acts together to promote follicular maturation, secrete estrogen, ovulation, and the production and maintenance of the corpus luteum, and secrete progesterone and estrogen.\u003c\/p\u003e \u003cp\u003eFor men, luteinizing hormone production facilitates the synthesis and release of testosterone by testicular stromal cells.\u003c\/p\u003e \u003c\/div\u003e \u003cdiv class=\"eximio-product-section eximio-clinical-significance\"\u003e \u003ch2 class=\"eximio-product-heading\"\u003eClinical Significance\u003c\/h2\u003e \u003cp\u003e1. Combined detection of serum LH and FSH: for women, it is mainly used to distinguish primary (ovarian) amenorrhea from secondary (pituitary) amenorrhea, in which serum LH is decreased.\u003c\/p\u003e \u003cp\u003eFor men, it is used to distinguish primary testicular dysfunction from secondary testicular dysfunction.\u003c\/p\u003e \u003cp\u003e2. Serum LH test can identify prepubertal children with true or false precocious puberty.\u003c\/p\u003e \u003cp\u003e3. The occurrence of LH peak in the menstrual cycle indicates the ovary ovulation within 24 to 36 hours. Therefore, monitoring the serum LH peak in the middle of menstruation can determine the best time for conception.\u003c\/p\u003e \u003cp\u003e4. Increased serum LH is found in polycystic ovary syndrome (persistent anovulation and excess androgens, etc.), Turner syndrome, primary hypogonadism, premature ovarian failure, post-ovary resection, and menopausal syndrome or postmenopausal women.\u003c\/p\u003e \u003cp\u003e5.LH also decreased after long-term use of birth control pills and hormone replacement therapy.\u003c\/p\u003e \u003c\/div\u003e \u003cdiv class=\"eximio-product-section eximio-product-parameters\"\u003e \u003ch2 class=\"eximio-product-heading\"\u003eProduct Parameters\u003c\/h2\u003e \u003cp\u003eThe main problem is the cross-reaction, cross-reaction with HCG, the cell line is easy to change.\u003c\/p\u003e \u003cdiv class=\"eximio-generated-table\" data-eximio-generated=\"product-info-xlsx\"\u003e\u003ctable class=\"eximio-product-specs eximio-product-table\"\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eMaterial \/ Clone\u003c\/th\u003e\n\u003cth\u003eType\u003c\/th\u003e\n\u003cth\u003eCode\u003c\/th\u003e\n\u003cth\u003eSource\u003c\/th\u003e\n\u003cth\u003eApplication\u003c\/th\u003e\n\u003cth\u003eRecommended Use\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eLH-9F1(β chain)\u003c\/td\u003e\n\u003ctd\u003emAb\u003c\/td\u003e\n\u003ctd\u003eFBFS5\u003c\/td\u003e\n\u003ctd\u003eMouse (Antibody)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003eCoating\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLH-11D3(β chain)\u003c\/td\u003e\n\u003ctd\u003emAb\u003c\/td\u003e\n\u003ctd\u003eFBLH6\u003c\/td\u003e\n\u003ctd\u003eMouse (Antibody)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003eLabeling\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLH Antibody\u003c\/td\u003e\n\u003ctd\u003emAb\u003c\/td\u003e\n\u003ctd\u003eABLH9\u003c\/td\u003e\n\u003ctd\u003eMouse (Antibody)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003e-\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLH Antigen\u003c\/td\u003e\n\u003ctd\u003eAg\u003c\/td\u003e\n\u003ctd\u003eAALH2\u003c\/td\u003e\n\u003ctd\u003eE. coli (Antigen)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003e-\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003c\/div\u003e \u003c\/div\u003e \u003c\/div\u003e","brand":"EXIMIO BIOTEC","offers":[{"title":"Default Title","offer_id":47429298520220,"sku":null,"price":0.0,"currency_code":"CNY","in_stock":true}]}],"url":"https:\/\/exmbio.com\/collections\/reproductive-pregnancy.oembed","provider":"EXIMIO BIOTEC","version":"1.0","type":"link"}