{"product_id":"ctni","title":"Cardiac Troponin I (cTnI) Antibody \u0026 Antigen","description":"\u003cstyle data-eximio-product-css=\"blue-v3\"\u003e .eximio-product-description { --eximio-blue: #1f5fbf; --eximio-blue-dark: #123e73; --eximio-blue-soft: #f4f8fd; --eximio-text: #334155; --eximio-overview-text: #365777; --eximio-muted: #64748b; --eximio-line: #dbe5f1; --eximio-surface: #f8fafc; width: 100%; max-width: none; margin: 0; color: var(--eximio-text); font-size: 16px; line-height: 1.72; -webkit-font-smoothing: antialiased; } .eximio-product-description, .eximio-product-description * { box-sizing: border-box; } .eximio-product-description .eximio-product-section { margin: 0; padding: 25px 0; border: 0; background: transparent; } .eximio-product-description .eximio-product-section:first-child { padding-top: 0; } .eximio-product-description .eximio-product-overview { padding-bottom: 30px; } .eximio-product-description .eximio-product-heading { position: static; display: block; margin: 0 0 17px; 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} .eximio-product-description .eximio-product-table { display: block; overflow-x: auto; -webkit-overflow-scrolling: touch; } .eximio-product-description .eximio-product-table th, .eximio-product-description .eximio-product-table td { min-width: 120px; padding: 10px 12px; font-size: 13px; } } \u003c\/style\u003e \u003cdiv class=\"eximio-product-description eximio-product-description--v3\"\u003e \u003cdiv class=\"eximio-product-section eximio-background\"\u003e \u003ch2 class=\"eximio-product-heading\"\u003eBackground\u003c\/h2\u003e \u003cp\u003eCardiac troponin (cTn) is a cardiac muscle contraction regulating protein.\u003c\/p\u003e \u003cp\u003ecTn is composed of subunits of three different genes: cardiac troponin T (cTnT), cardiac troponin I (cTn I), and troponin C (cTnC).\u003c\/p\u003e \u003cp\u003eCurrently, cTnT and cTnI are used for ACS laboratory diagnosis.\u003c\/p\u003e \u003cp\u003eTroponin I(cTnI) is a protein commonly found in muscle tissue. Since cTnI has a unique amino acid sequence in its composition (31 amino acids more at the n-terminal than striated muscle), skeletal muscle, liver, kidney and other cellular damage does not affect the judgment of its results, so troponin I has good specificity.\u003c\/p\u003e \u003c\/div\u003e \u003cdiv class=\"eximio-product-section eximio-clinical-significance\"\u003e \u003ch2 class=\"eximio-product-heading\"\u003eClinical Significance\u003c\/h2\u003e \u003cp\u003eMyocardial troponin is a biomarker with the strongest specificity and high sensitivity for the diagnosis of myocardial injury or necrosis at present, and it is the best confirmed marker for the diagnosis of AMI at present. It also has an important clinical significance in the risk stratification of ACS.\u003c\/p\u003e \u003cp\u003eIn healthy people, there is no or very low content of cTnI in blood. When myocardial ischemia and hypoxia occur, degeneration and necrosis occur, cell membrane is damaged, and cTnI diffuses into the intercellular matrix, and appears in peripheral blood earlier.\u003c\/p\u003e \u003cp\u003ecTnI appears in peripheral blood 4~6h after the onset, and reaches a peak 12~48 hours after the onset.\u003c\/p\u003e \u003cp\u003eAfter the occurrence of severe MI, the plasma cTnI remains high for 4~10 days, with a long diagnostic window.\u003c\/p\u003e \u003c\/div\u003e \u003cdiv class=\"eximio-product-section eximio-product-parameters\"\u003e \u003ch2 class=\"eximio-product-heading\"\u003eProduct Parameters\u003c\/h2\u003e \u003cp\u003eMyocardial infarction is the earliest indicator.\u003c\/p\u003e \u003cp\u003eConsistent with Abbott, the normal range is less than 10pg\/ml.\u003c\/p\u003e \u003cdiv class=\"eximio-generated-table\" data-eximio-generated=\"product-info-xlsx\"\u003e\u003ctable class=\"eximio-product-specs eximio-product-table\"\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eMaterial \/ Clone\u003c\/th\u003e\n\u003cth\u003eType\u003c\/th\u003e\n\u003cth\u003eCode\u003c\/th\u003e\n\u003cth\u003eSource\u003c\/th\u003e\n\u003cth\u003eApplication\u003c\/th\u003e\n\u003cth\u003eRecommended Use\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003ecTnI Antigen\u003c\/td\u003e\n\u003ctd\u003erAg\u003c\/td\u003e\n\u003ctd\u003eFATI1\u003c\/td\u003e\n\u003ctd\u003eE. coli (Antigen)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003eQuality Control\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ecTnI-15C6\u003c\/td\u003e\n\u003ctd\u003emAb\u003c\/td\u003e\n\u003ctd\u003eFBTI0\u003c\/td\u003e\n\u003ctd\u003eMouse (Antibody)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003eCoating\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ecTnI-8D3\u003c\/td\u003e\n\u003ctd\u003emAb\u003c\/td\u003e\n\u003ctd\u003eFBTI1\u003c\/td\u003e\n\u003ctd\u003eMouse (Antibody)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003eLabeling\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ecTnI Antibody\u003c\/td\u003e\n\u003ctd\u003emAb\u003c\/td\u003e\n\u003ctd\u003eABTI5\u003c\/td\u003e\n\u003ctd\u003eMouse (Antibody)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003e-\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ecTnI Antigen\u003c\/td\u003e\n\u003ctd\u003eAg\u003c\/td\u003e\n\u003ctd\u003eAATI8\u003c\/td\u003e\n\u003ctd\u003eE. coli (Antigen)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003e-\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003c\/div\u003e \u003c\/div\u003e \u003c\/div\u003e","brand":"EXIMIO BIOTEC","offers":[{"title":"Default Title","offer_id":47429298716828,"sku":null,"price":0.0,"currency_code":"CNY","in_stock":true}],"url":"https:\/\/exmbio.com\/products\/ctni","provider":"EXIMIO BIOTEC","version":"1.0","type":"link"}