{"product_id":"h-fabp","title":"Cardiac Fatty Acid-Binding Protein (h-FABP) Antibody \u0026 Antigen","description":"\u003cstyle data-eximio-product-css=\"blue-v3\"\u003e .eximio-product-description { --eximio-blue: #1f5fbf; --eximio-blue-dark: #123e73; --eximio-blue-soft: #f4f8fd; --eximio-text: #334155; --eximio-overview-text: #365777; --eximio-muted: #64748b; --eximio-line: #dbe5f1; --eximio-surface: #f8fafc; width: 100%; max-width: none; margin: 0; color: var(--eximio-text); font-size: 16px; line-height: 1.72; -webkit-font-smoothing: antialiased; } .eximio-product-description, .eximio-product-description * { box-sizing: border-box; } .eximio-product-description .eximio-product-section { margin: 0; padding: 25px 0; border: 0; background: transparent; } .eximio-product-description .eximio-product-section:first-child { padding-top: 0; } .eximio-product-description .eximio-product-overview { padding-bottom: 30px; } .eximio-product-description .eximio-product-heading { position: static; display: block; margin: 0 0 17px; padding: 0 0 10px; color: var(--eximio-blue-dark); background: transparent; border: 0; border-bottom: 1px solid var(--eximio-line); border-radius: 0; font-size: clamp(19px, 1.7vw, 22px); font-weight: 650; line-height: 1.35; letter-spacing: -0.01em; } .eximio-product-description .eximio-product-heading::before, .eximio-product-description .eximio-product-heading::after { content: none !important; display: none !important; } .eximio-product-description p { margin: 0 0 13px; color: var(--eximio-text); background: transparent; } .eximio-product-description p:last-child { margin-bottom: 0; } .eximio-product-description .eximio-product-overview \u003e p { max-width: 920px; color: var(--eximio-overview-text); font-size: 17px; line-height: 1.82; } .eximio-product-description strong { color: var(--eximio-blue-dark); font-weight: 650; } .eximio-product-description ol, .eximio-product-description ul { margin: 10px 0 0; padding-left: 1.45em; } .eximio-product-description li { margin: 0 0 8px; padding-left: 4px; } .eximio-product-description li::marker { color: var(--eximio-blue); } .eximio-product-description .eximio-important-note, .eximio-product-description .eximio-background, .eximio-product-description .eximio-clinical-significance, .eximio-product-description .eximio-product-parameters, .eximio-product-description .eximio-application-scope, .eximio-product-description .eximio-storage { background: transparent; border: 0; border-radius: 0; } .eximio-product-description .eximio-product-table { width: 100%; max-width: 100%; margin: 16px 0 4px; border: 1px solid var(--eximio-line); border-radius: 8px; border-collapse: separate; border-spacing: 0; background: #ffffff; } .eximio-product-description .eximio-product-table th, .eximio-product-description .eximio-product-table td { padding: 12px 14px; border-right: 1px solid var(--eximio-line); border-bottom: 1px solid var(--eximio-line); vertical-align: top; text-align: left; font-size: 14px; line-height: 1.55; } .eximio-product-description .eximio-product-table th { color: var(--eximio-blue-dark); font-weight: 650; background: var(--eximio-blue-soft); } .eximio-product-description .eximio-product-table tbody td { background: #ffffff; } .eximio-product-description .eximio-product-table tbody tr:nth-child(even) td { background: var(--eximio-surface); } .eximio-product-description .eximio-product-table tr:last-child \u003e * { border-bottom: 0; } .eximio-product-description .eximio-product-table tr \u003e *:last-child { border-right: 0; } .eximio-product-description .eximio-product-table th[scope=\"row\"] { width: 32%; min-width: 150px; } @media (max-width: 749px) { .eximio-product-description { font-size: 15px; line-height: 1.68; } .eximio-product-description .eximio-product-section { padding: 21px 0; } .eximio-product-description .eximio-product-overview { padding-bottom: 25px; } .eximio-product-description .eximio-product-heading { margin-bottom: 13px; padding-bottom: 8px; font-size: 18px; } .eximio-product-description .eximio-product-overview \u003e p { font-size: 16px; line-height: 1.76; } .eximio-product-description .eximio-product-table { display: block; overflow-x: auto; -webkit-overflow-scrolling: touch; } .eximio-product-description .eximio-product-table th, .eximio-product-description .eximio-product-table td { min-width: 120px; padding: 10px 12px; font-size: 13px; } } \u003c\/style\u003e \u003cdiv class=\"eximio-product-description eximio-product-description--v3\"\u003e \u003cdiv class=\"eximio-product-section eximio-background\"\u003e \u003ch2 class=\"eximio-product-heading\"\u003eBackground\u003c\/h2\u003e \u003cp\u003eCardiac fatty acid binding protein (h-FABP) is a new type of cytosolic protein in the heart.\u003c\/p\u003e \u003cp\u003eIt is highly cardio specific (that is, expressed primarily in heart tissue) but is also present in low concentrations in tissues other than the heart.\u003c\/p\u003e \u003cp\u003eAfter the onset of myocardial ischemic injury, h-FABP can be detected in the blood as early as 1-3 hours after the onset of chest pain, peak at 6-8 hours and return to normal plasma levels within 24-30 hours.\u003c\/p\u003e \u003cp\u003eCardiac fatty acid binding cytoplasmic protein is composed of 132 amino acids with a molecular weight of 15kDa.\u003c\/p\u003e \u003cp\u003eThe heart type fatty acid binding protein (h-FABP) gene is located on chromosome I.\u003c\/p\u003e \u003cp\u003eIt is one of the most abundant proteins in the heart.\u003c\/p\u003e \u003cp\u003eHFABP binds two fatty acid molecules and is involved in the transport of aliphatic acyl coenzyme A, which is active in the oxidation process and thus generates energy in the mitochondria\u003c\/p\u003e \u003c\/div\u003e \u003cdiv class=\"eximio-product-section eximio-clinical-significance\"\u003e \u003ch2 class=\"eximio-product-heading\"\u003eClinical Significance\u003c\/h2\u003e \u003cp\u003e1) h-FABP can be rapidly released into the blood in the early stage of ACS, which has the time advantage for the diagnosis of ACS and the characteristics of high specificity, high sensitivity and high coincidence rate for myocardial injury.\u003c\/p\u003e \u003cp\u003e2) In the long-term prognosis of ACS, h-FABP concentration can effectively identify high-risk patients with AMI, heart failure, unstable angina and other adverse events.\u003c\/p\u003e \u003cp\u003e3) the combined detection of h-FABP and troponin can improve the diagnostic sensitivity and have more diagnostic value for ACS.\u003c\/p\u003e \u003cp\u003eAs an early marker of myocardial injury, h-FABP could only detect with polyclonal antibodies with low specificity at the early stage, but the effect was not good.\u003c\/p\u003e \u003cp\u003eWith the application of highly specific monoclonal antibodies, h-FABP has been widely recognized in the early diagnosis and prognosis evaluation of ACS.\u003c\/p\u003e \u003cp\u003eCombined detection with troponin is the focus of clinical diagnosis in the future.\u003c\/p\u003e \u003c\/div\u003e \u003cdiv class=\"eximio-product-section eximio-product-parameters\"\u003e \u003ch2 class=\"eximio-product-heading\"\u003eProduct Parameters\u003c\/h2\u003e \u003cp\u003eThe Cutoff for 7-10 ng\/ml.\u003c\/p\u003e \u003cp\u003eIn turbidity market, the performance has good correlation, sensitivity and clinical matching consistency.\u003c\/p\u003e \u003cdiv class=\"eximio-generated-table\" data-eximio-generated=\"product-info-xlsx\"\u003e\u003ctable class=\"eximio-product-specs eximio-product-table\"\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eMaterial \/ Clone\u003c\/th\u003e\n\u003cth\u003eType\u003c\/th\u003e\n\u003cth\u003eCode\u003c\/th\u003e\n\u003cth\u003eSource\u003c\/th\u003e\n\u003cth\u003eApplication\u003c\/th\u003e\n\u003cth\u003eRecommended Use\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eh-FABP-B11\u003c\/td\u003e\n\u003ctd\u003emAb\u003c\/td\u003e\n\u003ctd\u003eFBHF1\u003c\/td\u003e\n\u003ctd\u003eMouse (Antibody)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003eLabeling\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eh-FABP-2F9\u003c\/td\u003e\n\u003ctd\u003emAb\u003c\/td\u003e\n\u003ctd\u003eFBHF2\u003c\/td\u003e\n\u003ctd\u003eMouse (Antibody)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003eCoating\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eH-FABP Antibody\u003c\/td\u003e\n\u003ctd\u003emAb\u003c\/td\u003e\n\u003ctd\u003eABHF7\u003c\/td\u003e\n\u003ctd\u003eMouse (Antibody)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003e-\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eH-FABP Antigen\u003c\/td\u003e\n\u003ctd\u003eAg\u003c\/td\u003e\n\u003ctd\u003eAAHF4\u003c\/td\u003e\n\u003ctd\u003eE. coli (Antigen)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003e-\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eH-FABP Antigen\u003c\/td\u003e\n\u003ctd\u003erAg\u003c\/td\u003e\n\u003ctd\u003eOAHF6\u003c\/td\u003e\n\u003ctd\u003eE. coli (Antigen)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003e-\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eh-FABP Raw Material Set\u003c\/td\u003e\n\u003ctd\u003eRaw Material Set\u003c\/td\u003e\n\u003ctd\u003eRMHF9\u003c\/td\u003e\n\u003ctd\u003eMouse (Antibody)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003e-\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003c\/div\u003e \u003c\/div\u003e \u003c\/div\u003e","brand":"EXIMIO BIOTEC","offers":[{"title":"Default Title","offer_id":47429298618524,"sku":null,"price":0.0,"currency_code":"CNY","in_stock":true}],"url":"https:\/\/exmbio.com\/products\/h-fabp","provider":"EXIMIO BIOTEC","version":"1.0","type":"link"}