{"product_id":"mpo","title":"Myeloperoxidase (MPO) Antibody \u0026 Antigen","description":"\u003cstyle data-eximio-product-css=\"blue-v3\"\u003e .eximio-product-description { --eximio-blue: #1f5fbf; --eximio-blue-dark: #123e73; --eximio-blue-soft: #f4f8fd; --eximio-text: #334155; --eximio-overview-text: #365777; --eximio-muted: #64748b; --eximio-line: #dbe5f1; --eximio-surface: #f8fafc; width: 100%; max-width: none; margin: 0; color: var(--eximio-text); font-size: 16px; line-height: 1.72; -webkit-font-smoothing: antialiased; } .eximio-product-description, .eximio-product-description * { box-sizing: border-box; } .eximio-product-description .eximio-product-section { margin: 0; padding: 25px 0; border: 0; background: transparent; } .eximio-product-description .eximio-product-section:first-child { padding-top: 0; } .eximio-product-description .eximio-product-overview { padding-bottom: 30px; } .eximio-product-description .eximio-product-heading { position: static; display: block; margin: 0 0 17px; padding: 0 0 10px; color: var(--eximio-blue-dark); background: transparent; border: 0; border-bottom: 1px solid var(--eximio-line); border-radius: 0; font-size: clamp(19px, 1.7vw, 22px); font-weight: 650; line-height: 1.35; letter-spacing: -0.01em; } .eximio-product-description .eximio-product-heading::before, .eximio-product-description .eximio-product-heading::after { content: none !important; display: none !important; } .eximio-product-description p { margin: 0 0 13px; color: var(--eximio-text); background: transparent; } .eximio-product-description p:last-child { margin-bottom: 0; } .eximio-product-description .eximio-product-overview \u003e p { max-width: 920px; color: var(--eximio-overview-text); font-size: 17px; line-height: 1.82; } .eximio-product-description strong { color: var(--eximio-blue-dark); font-weight: 650; } .eximio-product-description ol, .eximio-product-description ul { margin: 10px 0 0; padding-left: 1.45em; } .eximio-product-description li { margin: 0 0 8px; padding-left: 4px; } .eximio-product-description li::marker { color: var(--eximio-blue); } .eximio-product-description .eximio-important-note, .eximio-product-description .eximio-background, .eximio-product-description .eximio-clinical-significance, .eximio-product-description .eximio-product-parameters, .eximio-product-description .eximio-application-scope, .eximio-product-description .eximio-storage { background: transparent; border: 0; border-radius: 0; } .eximio-product-description .eximio-product-table { width: 100%; max-width: 100%; margin: 16px 0 4px; border: 1px solid var(--eximio-line); border-radius: 8px; border-collapse: separate; border-spacing: 0; background: #ffffff; } .eximio-product-description .eximio-product-table th, .eximio-product-description .eximio-product-table td { padding: 12px 14px; border-right: 1px solid var(--eximio-line); border-bottom: 1px solid var(--eximio-line); vertical-align: top; text-align: left; font-size: 14px; line-height: 1.55; } .eximio-product-description .eximio-product-table th { color: var(--eximio-blue-dark); font-weight: 650; background: var(--eximio-blue-soft); } .eximio-product-description .eximio-product-table tbody td { background: #ffffff; } .eximio-product-description .eximio-product-table tbody tr:nth-child(even) td { background: var(--eximio-surface); } .eximio-product-description .eximio-product-table tr:last-child \u003e * { border-bottom: 0; } .eximio-product-description .eximio-product-table tr \u003e *:last-child { border-right: 0; } .eximio-product-description .eximio-product-table th[scope=\"row\"] { width: 32%; min-width: 150px; } @media (max-width: 749px) { .eximio-product-description { font-size: 15px; line-height: 1.68; } .eximio-product-description .eximio-product-section { padding: 21px 0; } .eximio-product-description .eximio-product-overview { padding-bottom: 25px; } .eximio-product-description .eximio-product-heading { margin-bottom: 13px; padding-bottom: 8px; font-size: 18px; } .eximio-product-description .eximio-product-overview \u003e p { font-size: 16px; line-height: 1.76; } .eximio-product-description .eximio-product-table { display: block; overflow-x: auto; -webkit-overflow-scrolling: touch; } .eximio-product-description .eximio-product-table th, .eximio-product-description .eximio-product-table td { min-width: 120px; padding: 10px 12px; font-size: 13px; } } \u003c\/style\u003e \u003cdiv class=\"eximio-product-description eximio-product-description--v3\"\u003e \u003cdiv class=\"eximio-product-section eximio-background\"\u003e \u003ch2 class=\"eximio-product-heading\"\u003eBackground\u003c\/h2\u003e \u003cp\u003eMyeloperoxidase (MPO), also known as peroxidase, is a member of the heme superfamily.\u003c\/p\u003e \u003cp\u003eExists in myeloid cells, (mainly neutrophils and monocytes) of aniline blue particles, they are symbols of the specificity of myeloid cells. With the deepening of the research on MPO, MPO gene polymorphism has been found to cause the individual to some differences in disease susceptibility, closely related with the occurrence and development of human diseases. Thus, it gets more and more attention of scholars both at home and abroad.\u003c\/p\u003e \u003c\/div\u003e \u003cdiv class=\"eximio-product-section eximio-clinical-significance\"\u003e \u003ch2 class=\"eximio-product-heading\"\u003eClinical Significance\u003c\/h2\u003e \u003cp\u003e1..MPO is involved in all stages of atherosclerosis and plaque development in blood vessels.\u003c\/p\u003e \u003cp\u003e2. It leads to endothelial cell functional damage and promote plaque formation.\u003c\/p\u003e \u003cp\u003e3. It causes plaque instability, which leads to thinning of fibrous cap, plaque rupture and thrombosis.\u003c\/p\u003e \u003cp\u003e4. A large number of literature data show that MPO can be used as a predictor of coronary artery disease and acute coronary syndrome prognostic indicators: elevated MPO exist coronary artery in patients with inflammatory, plaque instability, but not completely blocked blood vessels, which does not cause myocardial necrosis. With early identification of unstable plaque, MPO is one of the inflammatory markers in early diagnosis of ACS.\u003c\/p\u003e \u003cp\u003e5. MPO, as a new inflammatory marker for the prediction of ACS, can identify the risk of future adverse cardiovascular events in patients with cardiac troponin T(cTnT) negative ACS.\u003c\/p\u003e \u003cp\u003e6. Foreign literature indicates that the baseline level of MPO can independently predict the risk of adverse cardiac events (myocardial infarction, re-infarction, vascular remodeling or death) in the next 30 days to 6 months.\u003c\/p\u003e \u003cp\u003e7. MPO can recognize patients with poor prognosis of ACS with low levels of c-reactive protein (CRP negative).\u003c\/p\u003e \u003cp\u003e8. It can predict the future risk of cardiovascular disease in healthy people over 35 years old\u003c\/p\u003e \u003cp\u003eMPO is independent from c-reactive protein and other inflammatory markers in determining a healthy person's future risk of cardiovascular disease.\u003c\/p\u003e \u003cp\u003eA study published in the prestigious New England journal of medicine in 2003 shows that by measuring MPO levels in 604 patients with chest pain, it can predict the likelihood of cardiovascular events over 30 days to six months.\u003c\/p\u003e \u003cp\u003eWhen cTnT was tested alone, only 54% of patients were predicted, while the probability of predicting with MPO increased to 84.5%.\u003c\/p\u003e \u003c\/div\u003e \u003cdiv class=\"eximio-product-section eximio-product-parameters\"\u003e \u003ch2 class=\"eximio-product-heading\"\u003eProduct Parameters\u003c\/h2\u003e \u003cp\u003eMarket trends: enzymatic, predictive (1-2 months ahead)\u003c\/p\u003e \u003cdiv class=\"eximio-generated-table\" data-eximio-generated=\"product-info-xlsx\"\u003e\u003ctable class=\"eximio-product-specs eximio-product-table\"\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eMaterial \/ Clone\u003c\/th\u003e\n\u003cth\u003eType\u003c\/th\u003e\n\u003cth\u003eCode\u003c\/th\u003e\n\u003cth\u003eSource\u003c\/th\u003e\n\u003cth\u003eApplication\u003c\/th\u003e\n\u003cth\u003eRecommended Use\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eMPO-2A7\u003c\/td\u003e\n\u003ctd\u003emAb\u003c\/td\u003e\n\u003ctd\u003eFBDD1\u003c\/td\u003e\n\u003ctd\u003eMouse (Antibody)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003eLabeling\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMPO-2E9\u003c\/td\u003e\n\u003ctd\u003emAb\u003c\/td\u003e\n\u003ctd\u003eFBMP2\u003c\/td\u003e\n\u003ctd\u003eMouse (Antibody)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003eCoating\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMPO Antibody\u003c\/td\u003e\n\u003ctd\u003emAb\u003c\/td\u003e\n\u003ctd\u003eABMP5\u003c\/td\u003e\n\u003ctd\u003eMouse (Antibody)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003e-\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMPO Antigen\u003c\/td\u003e\n\u003ctd\u003eAg\u003c\/td\u003e\n\u003ctd\u003eAAMP7\u003c\/td\u003e\n\u003ctd\u003eE. coli (Antigen)\u003c\/td\u003e\n\u003ctd\u003eEIA, LF\u003c\/td\u003e\n\u003ctd\u003e-\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003c\/div\u003e \u003c\/div\u003e \u003c\/div\u003e","brand":"EXIMIO BIOTEC","offers":[{"title":"Default Title","offer_id":47429298782364,"sku":null,"price":0.0,"currency_code":"CNY","in_stock":true}],"url":"https:\/\/exmbio.com\/products\/mpo","provider":"EXIMIO BIOTEC","version":"1.0","type":"link"}