From Diagnostic Concept to Assay Development
EXIMIO provides contract development support for IVD projects, connecting diagnostic raw material evaluation, antibody screening, assay development and performance optimization within a practical development workflow.
Development Support Built Around IVD Projects
Diagnostic assay development requires more than identifying a biomarker. Raw materials must be screened, reagent combinations compared, molecular interactions understood where appropriate, and selected candidates tested within the intended assay format.
EXIMIO integrates diagnostic biomaterials with practical evaluation and assay development capabilities to support projects from early material selection through assay optimization and development-stage verification.
The development pathway can be adapted according to project stage, existing materials, assay format and technical objectives.
Support Across Key Assay Development Stages
Services can be configured around individual technical questions or connected into a broader development program.
Project & Feasibility Assessment
Review assay objectives, target analytes, available raw materials, detection format and development requirements before experimental evaluation begins.
Diagnostic Material Screening
Compare candidate antigens, antibodies and relevant reagents to identify materials suitable for subsequent assay development.
Antibody Pair Evaluation
Support clone comparison, paired-antibody screening and antigen-antibody evaluation using appropriate analytical and assay platforms.
Assay Development
Translate selected materials into practical immunoassay formats and evaluate reagent combinations under relevant test conditions.
Performance Optimization
Use experimental results to guide optimization of material combinations, assay conditions, signal systems and practical performance.
Development-Stage Verification
Review selected assay configurations through project-appropriate evaluation before subsequent scale-up, manufacturing or further validation activities.
A Connected Path from Technical Question to Assay
Rather than treating material evaluation and assay development as isolated steps, the workflow connects experimental findings with subsequent development decisions.
Define
Clarify target, format and development objectives.
Screen
Compare relevant diagnostic raw materials.
Evaluate
Review reactivity and molecular interactions.
Develop
Build selected materials into an assay format.
Optimize
Adjust reagents, conditions and signal response.
Verify
Review development-stage assay performance.
Three Platforms, Complementary Technical Perspectives
Different development questions require different evaluation approaches. ELISA, lateral flow immunoassay and Bio-Layer Interferometry can provide complementary information across material screening, interaction analysis and practical assay evaluation.
PLATFORM 01
ELISA
Plate-based evaluation provides a practical approach for reviewing antigen-antibody reactivity and immunoassay-oriented material performance during screening and comparison.
PLATFORM 02
Lateral Flow Immunoassay
Selected diagnostic materials can be evaluated directly in a rapid-test format using colloidal gold or fluorescent conjugate approaches according to project requirements.
PLATFORM 03
Bio-Layer Interferometry
Real-time, label-free molecular interaction analysis provides additional information for antibody evaluation, clone comparison and relevant biomaterial characterization.
From Molecular Interaction to Practical Assay Performance
No single analytical method answers every development question. EXIMIO combines different technical perspectives so that evaluation results can support subsequent assay development decisions.
Screen Materials
Compare relevant candidate antibodies, antigens and other diagnostic reagents.
Evaluate Interactions
Review antigen-antibody or other relevant molecular interaction behavior where appropriate.
Test in Assay Format
Assess selected materials under practical immunoassay conditions.
Use Data to Optimize
Apply evaluation findings to guide reagent combinations and subsequent development work.
Flexible Support for Different Development Starting Points
Projects do not always begin at the same stage. Development support can focus on a specific technical challenge or connect multiple stages within a broader program.
Raw Material Selection
Support projects that require comparison or selection of antigens, antibodies and other diagnostic biomaterials before assay development.
Existing Assay Optimization
Evaluate selected materials, reagent combinations or interaction behavior to support troubleshooting and further optimization of an existing assay.
New Assay Development
Connect raw material evaluation with practical assay development when a project is moving from concept toward a working diagnostic format.
Development-to-Manufacturing Transition
Organize development-stage information and selected assay configurations for subsequent process transfer, scale-up or CMO discussions.
Have a Diagnostic Assay in Development?
Tell us about your target, current materials, assay format and technical objective. Our team can discuss an evaluation and development approach based on your project stage.