Canine C-Reactive Protein (cCRP) Antibody & Antigen
Canine C-Reactive Protein (cCRP) antibody and antigen raw materials for immunoassay development, reagent screening and rapid-test optimization. Source: Mouse (Antibody) / E. coli (Antigen); application: Canine Inflammation / Infection Assessment.
Background
Canine C-reactive protein is an annular pentamer protein with a approximate molecular weight of 100kD which consists of five subunits. Different from huaman CRP, two subunits of cCRP is glycosylated. It is not easily soluble in water, its crystal is rhombus, may be precipitated by sodium sulfate, it is not heat resisting and will be damaged in 56℃ in 30minutes. Its half-time period is about 16 hours.
cCPR is an acute reactive protein.Its concentration is less than 5mg/L in a healthy dog. When organism is stimulated by inflammation ,infection or tissue damage, proinflammatory cytokine IL-6, IL-2 and TNF will induce liver to compose CRP. The level keep going up in 4-6 hours and reach to the peak in 24-28 hours. After inflammation disappears, CRP level go down by 50% in 24 hours. Therefore, CRP is an outstanding supervisor index in systemic inflammation and disease development.
Clinical Significance
cCPR can be used in diagnosis, treatment and detection of infectious diseases.
cCPR will increase gradually in traumatic disease, and decrease gradually after it reaches to the peak.
Though cCPR is not the only diagnostic index in neoplastic disease, it can be a detective index in the process in treatment and prognosis.
Product Parameters
| Material / Clone | Type | Code | Source | Detection Method | Recommended Use |
|---|---|---|---|---|---|
| cCRP Antibody | mAb | ABCR3 | Mouse (Antibody) | ELISA; ICA | - |
| cCRP Antigen | Ag | AACR37 | E. coli (Antigen) | ELISA; ICA | - |
| CCRP-1E9 | mAb | FBCR3 | Mouse (Antibody) | ELISA; ICA | Coating |
| CCRP-8H6 | mAb | FBCR2 | Mouse (Antibody) | ELISA; ICA | Labeling |
| cCRP Antigen | rAg | FACR2 | E. coli (Antigen) | ELISA; ICA | Quality Control |