Human C-Reactive Protein (CRP)
Human C-Reactive Protein (CRP) antibody raw material for immunoassay development, reagent screening and rapid-test optimization. Source: Mouse; application: Inflammation / Infection Assessment.
Background
C-reactive protein was first discovered in 1930. It is an acute reaction protein that can react to pneumococcal C polusacharide and become a compound. It is compounded mostly in the liver cells. The concentration of CRP in a normal adult is usually less than 10mg/L, Once the organism is stimulated by inflammation or tissue trauma, liver will immediately produce a lot of CRP, especially when the organism is infected by virus, about 96% patient’s body increases the level of CRP in a rapid speed. CRP is a very sensitive, non-specific mark of systemic inflammation, tissue trauma and infection. Prospective epidemiological study shows that the level of CRP is a strong, independent and predicable risk factor of people who have the disease of myocardial infarction, stroke, peripheral artery disease, no obvious cardiovascular disease, acute coronary syndrome and stable coronary artery disease (CAD). Besides, CRP is not very sensitive to the external factor such as age, gender or anemia. It has more advantages than other acute phase reactants in differentiating infantile pneumonia infection types.
Clinical Significance
1. The normal reference value of CRP is no more than 10mg/L, and the degree of increase of CRP reflects the size or activity of inflammatory tissue. In the case of acute inflammation and infection, CRP has a good correlation with disease activity.
2. A CRP value of 10-50mg/L indicates mild inflammation, such as local bacterial infections (such as cystitis, bronchitis, abscess), surgery and accidental trauma, myocardial infarction, deep vein thrombosis, inactive connective tissue disease, many malignancies, and most viral infections
3. A CRP value of about 100mg/L can indicate a serious disease and the presence of bacterial infection.
Product Parameters
Code: RMCR7
| Material / Clone | Type | Code | Source | Application | Recommended Use |
|---|---|---|---|---|---|
| CRP Raw Material Set | Raw Material Set | RMCR7 | Mouse | EIA, LF | - |