Infectious Bovine Rhinobronchitis (IBR)
IBR recombinant antigen raw material supports assay development for bovine herpesvirus-1 infection in cattle. The FAIB56 antigen is E. coli-expressed and is intended for ELISA and immunochromatographic assay development.
Background
Infectious bovine rhinobronchitis (IBR), also known as "necrotizing rhinitis", "red nose disease", is a type I bovine herpes virus (bhv-1) caused by a contact respiratory infection of cattle. Clinical manifestations are diverse, mainly in the respiratory tract, accompanied by conjunctivitis, abortion, mastitis, and sometimes induced encephalitis in calves.
Clinical Significance
The typical case of this disease (upper respiratory tract inflammation) has characteristic symptoms such as nasal mucosa congestion, pustules, dyspnea, nasal discharge pus, etc., combined with epidemiology, a preliminary diagnosis can be made, but the diagnosis must rely on laboratory diagnosis, including virus isolation and identification and serological test. Virus neutralization test (VN) and various enzyme-linked immunosorbent assay (ELISA) are commonly used to detect BHV1 antibody in serum samples. In addition, there are AGAR diffusion test and indirect hemagglutination test. Since IBRV infection is usually latent, identifying serologically positive animals is a useful and ideal indicator for testing the infection status of animals. Antibody positive animals can be considered as carriers of the virus and potential intermittent detoxers, except calves with maternal antibody from colostrum and non-infected cattle immunized with inactivated vaccine.
Product Parameters
| Material / Clone | Type | Code | Source | Detection Method | Recommended Use |
|---|---|---|---|---|---|
| G76 | rAg | FAIB56 | E. coli | ELISA; ICA | Labeling/Coating |