PCT
PCT antibody raw material for immunoassay development, reagent screening and rapid-test optimization. Source: Mouse; application: Bacterial Infection / Sepsis Assessment.
Background
PCT is a protein that is elevated in plasma during severe bacterial, fungal, and parasitic infections, as well as sepsis and multiple organ failure.
PCT does not increase with autoimmunity, allergy, or viral infection.
Limited local bacterial infection, mild infection and chronic inflammation will not lead to its elevation.
Bacterial endotoxin plays an important role in the induction process.
Clinical Significance
PCT reflects the level of systemic inflammatory response.
Factors that affect PCT levels include the size and type of organ being infected, the type of bacteria, the level of inflammation, and the state of the immune response.
In addition, PCT can only be detected in a small number of patients 1 to 4 days after major surgery.
Elevated PCT levels are seen in severe shock, systemic inflammatory response syndrome (SIRS), and multiple organ dysfunction syndrome (MODS), even without bacterial infection or bacterial lesions.
However, in these cases, PCT levels are usually lower than in patients with bacterial lesions.
Release of cytokines or bacterial translocation from the gut may induce induction.
Product Parameters
The specificity is very good, the cutoff value is 0.5ng-2ng, ang-10ng, greater than 10ng, our background is very clean, 0.0.5ng-0.5ng, the low value does not fluctuate.
Code: RMPC4
| Material / Clone | Type | Code | Source | Application | Recommended Use |
|---|---|---|---|---|---|
| PCT Raw Material Set | Raw Material Set | RMPC4 | Mouse | EIA, LF | - |