Porcine Circovirus (PCV)
Porcine Circovirus (PCV) recombinant antigen raw material supports veterinary assay development for PCV infection and PCV2-associated disease monitoring. The FAPC3 antigen is E. coli-expressed and is intended for ELISA and immunochromatographic assay development.
Product Parameters
| Parameter | Specification |
|---|---|
| Code | FAPC3 |
| Source | E. coli |
| Detection Method | ELISA; ICA |
Background
PCVPorcinecircovirus is one of the smallest animal viruses ever found. PCV is known to have two serotypes, namely PCV1 and PCV2. PCV1 was a non-pathogenic virus and PCV2 was a pathogenic virus. PCV2 is weaned piglets more system failure syndrome (PostweaningMultisystemicWastingSyndrome, PMWS), dermatitis and nephropathy syndrome (PNDS) the main pathogens, PMWS originally found in Canada.
Clinical Significance
1. Ⅱ F method appropriate to detect the PCV in cell cultures. Pk-15 cells were cultured with tissue material and covered glass, fixed with acetone, and PCV was detected and classified by the reaction of rabbit anti-pcv serum with PCV in cell culture.
2.ELISA can be used to detect virus antibodies in serum. Using cell culture virus (PCV2) as antigen and PCV2 specific monoclonal antibody as competitive reagent to establish competitive ELISA method, the detection rate of competitive ELISA method was 99.58%, while the detection rate of indirect immunofluorescence method was only 97.14%. This method can be used for large-scale monitoring of PCV2 antibody.